The BIOFIRE System and Your Immune System

The BIOFIRE System offers syndromic testing for infectious illnesses, allowing healthcare professionals to select the appropriate test first time. Patients benefit from faster diagnosis and a more targeted treatment. Clinicians benefit from improved stewardship of antibiotics. Labs save money and increase efficiency.

The BioFire Pneumonia Plus Panel (PN panel) tests native sputum (including mini-BAL) as well as endotracheal sludge and bronchoalveolar liquids (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour.

Respiratory

The burning of biomass, such as wood, plants and other organic materials produces gaseous pollutants and fine particles that negatively affect the respiratory system. Furthermore, the environmental issues caused by forest fires, like droughts, could be amplified by climate change, thereby increasing their negative impact on the health of humans.

In the United States, wildfire smoke has been linked to hospitalizations for respiratory illnesses, including asthma, COPD and lung cancer. Additionally, this kind of air pollution is an important risk factor for cardiovascular disease and is a significant contributing factor to the burden of illness among the most vulnerable populations that include those with lower socioeconomic status (SES).

Wildfires have led to unhealthy levels of air pollution in numerous communities during the COVID-19 epidemic. However the response of public health officials to this environmental problem is sporadic and mainly focused on communicating about symptom management. This lack of knowledge is concerning given the evidence of potential health hazards from the continued exposure to smoke and other sources of poor air quality.

Researchers are now looking at the best ways to safeguard the public's health in future events similar to this. NIH is a research institution that studies this crucial public health issue through the BLUE CORAL and indoor bio ethanol fire CORAL studies.

For the first time an prospective cohort study will examine long-term effects resulting from exposure to smoke from wildfires as well as other sources. bio ethanal fire CORAL recruits adult participants who are admitted to hospital for COVID-19 index episodes and who speak English or Spanish however, they are not pregnant. The protocol for FIRE CORAL includes a set of tests in-person that objectively measure pulmonary function testing and lung imaging as well as functional assessment.

The lungs are the most sensitive to the effects of smoke and other particles due to the fact that they can trigger or exacerbate chronic respiratory diseases such as emphysema, asthma and COPD and increase the risk of pneumonia. Smoke exposure can have negative consequences for health. To minimize or avoid these negative effects, avoid outdoor activities and wear the EPA "N95" mask. The mask is designed to capture small particles.

Smoking can also cause irritation to the eyes, throat and nose. To minimize symptoms, drink lots of water and take medications that reduce inflammation, such as corticosteroids.

Bloodstream

Your bloodstream is at the forefront of fighting off germs that enter your body. Special cells called dendritic cells are like the fire department's call center; they collect the antigens (molecules that trigger an immune response) from invading germs and release proteins that alert other white blood cells to come fight them. The white blood cell counts, differentials and band cells were increased following firefighters' fire-fighting shifts, and compared to levels following strenuous physical exercise with no firefighting.

Skin

Dermatologists were concerned about the smoke and ash of the California wildfires could cause an adverse effect on the skin of those who were exposed to them. Maria Wei is a graduate student at the University of California, Irvine. She examines how extreme wildfire pollution affects the skin. Her research was published in Scientific Reports on April 22.

The study of Wei shows that the temperature changes of the skin according to the length of time the body has been exposed. It can take up to two hours for a skin to reach its flash point -- the temperature at which it starts to burn and turns to ash. This is the reason why it's essential to avoid being near a fire or campfire, and why you should wear protective clothing if you are outdoors during a forest fire or even on an extremely hot day.

Forest fires will continue happen, despite the precautions taken to prevent fires from causing pollution. Wei believes that as the climate changes cause forests to burn faster, the number of people who suffer from wildfires will increase. This means that more people will have to wear hats and long sleeves as well as thick moisturizers.

It's also important to know that atopic dermatitis (itchy skin) that many people suffer from can be exacerbated by wildfire air pollution. The reason for this is due to smoke particles can clog pores, thereby making the atopic dermatitis condition worse.

Another issue is the fact that atopic dermatitis can make people more sensitive to UV light, which can also be aggravated by wildfire smoke. This could lead to people looking for tanning salons and apply a tan with less protection.

While a ice and fire facial may help reduce the effects of atopic skin dermatitis, it's not recommended for anyone who has an open wound or a rash on their face. This treatment is not recommended for those who have active acne, or if you are pregnant or nursing. The IS Clinical Fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa, is an intensive, results-driven facial that bridges the gap between a gentle facial and a peel, without requiring any downtime. It's designed to resurface the skin, bioethanol fires alleviate rosacea symptoms, decrease acne scarring, reduce wrinkles, and promote cell renewal. This is a great way to provide your skin with a radiant glow.

Infections

The human body is made up of a complex set of organs and tissues that work together in order to defend us from infections. Infections can be caused by microorganisms such as bacteria, viruses and parasites that infect healthy cells and cause them to multiply in uncontrolled ways. Your immune system could react by displaying symptoms of illness. The symptoms could include a runny nose to a stomach that is upset as well as a fever, swollen lymph glands, or an itchy rash. Your symptoms can be affected by the nature of the infection, its location and even your temperature.

Infections can spread in various ways, but they are most often spread via droplets of air that remain after a sniff or cough. This is how bacterial illnesses like tuberculosis, strep, and meningococcal illness and viral infections such a common cold and influenza, are spread. Some bacterial infections such as skin infections or sexually transmitted diseases (STIs) like chlamydia or gonorrhea are transmitted by direct contact with infected mucous or tissue surfaces, or indirectly through contaminated surfaces. Some bacterial infections are spread by insects such as ticks, fleas, or mosquitoes.

Some parasites and viruses are small bio ethanol fires enough to get into your bloodstream and infect your cells which can cause serious illness like the common cold or AIDS. Fungi can cause a variety of skin ailments such as ringworm, athlete's foot. Other types affect the lungs or the nervous system, such as the rabies virus.

The BioFire Panel uses our innovative FilmArray Technology to test the sputum and bronchoalveolar fluid samples to determine a comprehensive list of pathogens involved in upper respiratory infection. The kit includes a reagent pouch that stores all the necessary chemistry to perform reverse transcription PCR, nested multiplex PCR and detection with a single device. This is a straightforward solution that assists clinicians identify and treat patients with several respiratory symptoms. This test has been given an Emergency Use Authorization. It's available in bioMerieux CLIA medium and high-complex laboratories.